Interspecies conservation of organisation and function between nonhomologous regional centromeres
oleh: Pin Tong, Alison L. Pidoux, Nicholas R. T. Toda, Ryan Ard, Harald Berger, Manu Shukla, Jesus Torres-Garcia, Carolin A. Müller, Conrad A. Nieduszynski, Robin C. Allshire
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-05-01 |
Deskripsi
Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosaccharomyces centromere DNA possesses intrinsic conserved properties that promote assembly of CENP-A chromatin.