Tuberculosis Variant with Rifampin Resistance Undetectable by Xpert MTB/RIF, Botswana
oleh: Chawangwa Modongo, Ivan Barilar, Qiao Wang, Tuduetso Molefi, Topo Makhondo, Stefan Niemann, Sanghyuk S. Shin
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2023-11-01 |
Deskripsi
GeneXpert MTB/RIF, a tool widely used for diagnosing tuberculosis, has limitations for detecting rifampin resistance in certain variants. We report transmission of a pre–extensively drug-resistant variant in Botswana that went undetected by GeneXpert. The public health impact of misdiagnosis emphasizes the need for comprehensive molecular testing to identify resistance and guide treatment.