Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics
oleh: Jiawei Huang, Jie Sheng, Daifeng Wang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Huang et al apply and benchmark multiple machine learning methods to align gene expression and electrophysiological data of single neuronal cells in the mouse brain from the Brain Initiative. Their approach reveals potential genome functions and gene regulatory mechanisms from gene expression to neuronal electrophysiology.