Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation

oleh: Komal Soni, Georg Kempf, Karen Manalastas-Cantos, Astrid Hendricks, Dirk Flemming, Julien Guizetti, Bernd Simon, Friedrich Frischknecht, Dmitri I. Svergun, Klemens Wild, Irmgard Sinning

Format: Article
Diterbitkan: Nature Portfolio 2021-05-01

Deskripsi

The SRP Alu domain is involved in co-translational protein targeting. Soni et al. investigate the Alu domain of Plasmodium falciparum, the agent of malaria, and find that unlike any other it adopts an open conformation.