Structure and mechanism of DNA delivery of a gene transfer agent

oleh: Pavol Bárdy, Tibor Füzik, Dominik Hrebík, Roman Pantůček, J. Thomas Beatty, Pavel Plevka

Format: Article
Diterbitkan: Nature Portfolio 2020-06-01

Deskripsi

Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.