Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D

oleh: Antonia Grauel, Jan Kägi, Tim Rasmussen, Iryna Makarchuk, Sabrina Oppermann, Aurélien F. A. Moumbock, Daniel Wohlwend, Rolf Müller, Frederic Melin, Stefan Günther, Petra Hellwig, Bettina Böttcher, Thorsten Friedrich

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Terminal bd oxidases endow bacterial pathogens with resistance to cellular stressors. The authors report the structure of E. coli bd-II type oxidase with the bound inhibitor aurachin D, providing a structural basis for the design of specifically binding antibiotics.