Reduction of primary graft dysfunction using cytokine adsorption during organ preservation and after lung transplantation
oleh: Haider Ghaidan, Martin Stenlo, Anna Niroomand, Margareta Mittendorfer, Gabriel Hirdman, Nika Gvazava, Dag Edström, Iran A. N. Silva, Ellen Broberg, Oskar Hallgren, Franziska Olm, Darcy E. Wagner, Leif Pierre, Snejana Hyllén, Sandra Lindstedt
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-07-01 |
Deskripsi
Lung transplantation is hindered by the scarcity of organs and by mortality following primary graft dysfunction. Here, the authors show that cytokine absorption can be used in donor lungs during ex vivo lung perfusion and post-transplant, and leads to restored lung function and reduced primary graft dysfunction in animal models.