Single-molecule imaging of UvrA and UvrB recruitment to DNA lesions in living Escherichia coli
oleh: Mathew Stracy, Marcin Jaciuk, Stephan Uphoff, Achillefs N. Kapanidis, Marcin Nowotny, David J. Sherratt, Pawel Zawadzki
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Nucleotide excision repair is able to identify and remove a wide range of DNA helix distorting lesions from the genome. Here the authors use single molecule imaging of UvrA and UvrB molecules and suggest a two-step ‘scan and recruit’ model for UvrA function.