Maturation and specialization of group 2 innate lymphoid cells through the lung-gut axis

oleh: Min Zhao, Fei Shao, Dou Yu, Jiaqi Zhang, Zhen Liu, Jiangwen Ma, Pengyan Xia, Shuo Wang

Format: Article
Diterbitkan: Nature Portfolio 2022-12-01

Deskripsi

The developmental process of group 2 innate lymphoid cells (ILC2) involves migration between different internal organs. Here the authors show that ILC2s migrate from the lung to the intestine to undergo maturation after treatment with IL-33 and that lung and intestine ILC2s have a different phenotype.