Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march

oleh: Justine Segaud, Wenjin Yao, Pierre Marschall, François Daubeuf, Christine Lehalle, Beatriz German, Pierre Meyer, Pierre Hener, Cécile Hugel, Eric Flatter, Marine Guivarch, Laetitia Clauss, Stefan F. Martin, Mustapha Oulad-Abdelghani, Mei Li

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

Allergic sensitisation in the skin can lead to allergic dermatitis and further to airway asthma in a process of atopic march. Here the authors examine the difference between superficial or deep skin sensitisation, characterise the immune cells generated and show differential TSLP and IL-1β involvement.