Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters
oleh: Brandi N. Williamson, Joseph Prescott, Jose L. Garrido, Raymond A. Alvarez, Heinz Feldmann, Maria I. Barría
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2021-10-01 |
Deskripsi
Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. We show that a combined treatment with 2 monoclonal antibodies protected Syrian hamsters when administered at midstage or late-stage disease.