NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ
oleh: Jianfeng Huang, Juan F. Linares, Angeles Duran, Wenmin Xia, Alan R. Saltiel, Timo D. Müller, Maria T. Diaz-Meco, Jorge Moscat
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-05-01 |
Deskripsi
p62 is a signaling hub protein that contributes to the control of energy expenditure. Here the authors investigate the relative roles of p62 and a similar protein, NBR1, and show that NBR1 is required for the repression of thermogenesis in adipocytes occurring in the absence of p62.