Find in Library

Rh blood group is one of the most complexes of the human blood groups system. RHD gene encodes the D antigen, and the RHCE encodes the C, c, E, and e antigens. Out of these, Rh D antigen is the most immunogenic while e antigen is the least immunogenic. Rh antibodies are produced in Rh-negative individuals following sensitization which occurs either through pregnancy or during blood transfusion. We hereby report two cases of anti-e antibody, both presenting as major crossmatch incompatibility.