Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Cerebral vasculitis due to Aspergillus spp. in immunocompromised patients: literature review
oleh: Elie Haddad, Arnaud Fekkar, Sophie Bonnin, Natalia Shor, Danielle Seilhean, Isabelle Plu, Valérie Touitou, Véronique Leblond, Nicolas Weiss, Sophie Demeret, Valérie Pourcher
Format: | Article |
---|---|
Diterbitkan: | Elsevier 2022-09-01 |
Deskripsi
Objectives: Invasive aspergillosis is a threat for immunocompromised patients. We present a case series of aggressive cerebral vasculitis caused by Aspergillus spp. infection in immunocompromised patients. Methods: We present a retrospective case series of three autopsy-proven invasive cerebral aspergillosis with diffuse vasculitis affecting large caliber cerebral vessels. Results: Three patients were immunosuppressed: one on rituximab, one on corticosteroids, and one with a renal transplant. Two of these patients were diagnosed with cerebral aspergillosis on postmortem. Conclusion: Aspergillus cerebral vasculitis is a rare form of invasive aspergillosis that should be considered in an immunocompromised individual with suggestive lesions on imaging. It should be suspected as a possible cause of aseptic neutrophil meningitis.