The H2A.Z histone variant integrates Wnt signaling in intestinal epithelial homeostasis
oleh: Jérémie Rispal, Lucie Baron, Jean-François Beaulieu, Martine Chevillard-Briet, Didier Trouche, Fabrice Escaffit
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-04-01 |
Deskripsi
The histone variant, H2A.Z is known to regulate gene expression and cell proliferation. Here the authors show that H2A.Z has a central role in the control of intestinal epithelial homeostasis in mice, by preventing terminal differentiation of intestinal progenitors.