Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
oleh: Wint Wint Phoo, Yan Li, Zhenzhen Zhang, Michelle Yueqi Lee, Ying Ru Loh, Yaw Bia Tan, Elizabeth Yihui Ng, Julien Lescar, CongBao Kang, Dahai Luo
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
The proteases of flaviviruses are promising targets for development of specific antiviral drugs. Here, the authors report a high resolution crystal structure of the NS2B-NS3 protease of Zika virus that provides insight into substrate and inhibitor binding.