Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance
oleh: Masaru Usui, Yutaka Yoshii, Stanislas Thiriet-Rupert, Jean-Marc Ghigo, Christophe Beloin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Mutations in sbmA and fusA are rapidly selected in biofilm but not planktonic E. coli when exposed to intermittent amikacin antibiotic treatment, which suggests that the biofilm environment favors rapid evolution of resistance.