Frequent miRNA-convergent fusion gene events in breast cancer
oleh: Helena Persson, Rolf Søkilde, Jari Häkkinen, Anna Chiara Pirona, Johan Vallon-Christersson, Anders Kvist, Fredrik Mertens, Åke Borg, Felix Mitelman, Mattias Höglund, Carlos Rovira
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-10-01 |
Deskripsi
Fusion gene research traditionally focuses on fusions that result in hybrid proteins or promoter switching events. Here, the authors demonstrate enrichment of fusions in miRNA host genes in breast cancer, highlighting that disparate fusions could have convergent impact on miRNA.