Common mechanism of transcription termination at coding and noncoding RNA genes in fission yeast

Yazar:: Marc Larochelle, Marc-Antoine Robert, Jean-Nicolas Hébert, Xiaochuan Liu, Dominick Matteau, Sébastien Rodrigue, Bin Tian, Pierre-Étienne Jacques, François Bachand

Materyal Türü: Article
Baskı/Yayın Bilgisi: Nature Portfolio 2018-10-01

Diğer Bilgiler

Termination of RNA polymerase II (RNAPII) transcription is an essential step of gene expression. Here the authors provide evidence that in fission yeast termination of ncRNA genes occurs by a cleavage-dependent mechanism involving recruitment of mRNA 3′ end processing factors and requires the conserved Ysh1/CPSF-73 and Dhp1/XRN2 nucleases.