p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
oleh: Kasumi Murai, Stefan Dentro, Swee Hoe Ong, Roshan Sood, David Fernandez-Antoran, Albert Herms, Vasiliki Kostiou, Irina Abnizova, Benjamin A. Hall, Moritz Gerstung, Philip H. Jones
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Ageing normal oesophagus epithelium contains p53 mutant clones. Here the authors use transgenic mice to show how these clones form and contribute to cancer development.