Generation of an induced pluripotent stem cell line AMUFAHi002-A from polycystic ovary syndrome patient

oleh: Xiaohua Jiang, Ruomeng Hu, Caihua Li, Xuan Xu, Ping Zhou, Yunxia Cao, Jianye Wang, Zhaolian Wei

Format: Article
Diterbitkan: Elsevier 2022-08-01

Deskripsi

Polycystic ovary syndrome (PCOS) is one of the most prevalent endocrine disorders in women of reproductive age. The PCOS leads to obesity, dyslipidemia, insulin resistance, hyperandrogenism, and infertility. We established an induced pluripotent stem cell line (iPSC) from a PCOS patient. This disease-specific iPSC line will be beneficial to study PCOS in vitro, allowing to understand the pathogenic mechanisms and a cell-based model for drug development for PCOS.