Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

oleh: Laila Shehata, Wendy F. Wieland-Alter, Daniel P. Maurer, Eunice Chen, Ruth I. Connor, Peter F. Wright, Laura M. Walker

Format: Article
Diterbitkan: Nature Portfolio 2019-03-01

Deskripsi

Here, the authors isolate over 800 RSV F-specific antibodies from paired nasopharyngeal tonsil and peripheral blood samples from four young children undergoing adenoidectomy and find that adenoid derived antibodies have overall higher binding affinities and neutralization potencies.