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Structural insights into the committed step of bacterial phospholipid biosynthesis
oleh: Zhenjian Li, Yannan Tang, Yiran Wu, Suwen Zhao, Juan Bao, Yitian Luo, Dianfan Li
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
The first step in bacterial phospholipid biosynthesis is the acylation of glycerol 3-phosphate to form lysophosphatidic acid. Here, the authors present the high resolution crystal structure of the glycerol 3-phosphate acyltransferase PlsY, a membrane protein and give insights into its catalytical mechanism.