Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis
oleh: Takashi Hirama, Stella M. Lu, Jason G. Kay, Masashi Maekawa, Michael M. Kozlov, Sergio Grinstein, Gregory D. Fairn
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
The plasma membrane is enriched in phosphatidylserine (PtdSer) mostly localized at the inner leaflet, which is predicted to induce membrane curvature. Here the authors show that membrane curvature induced by the proximity of anionic phospholipids can induce endocytosis and that cholesterol limits spontaneous curvature.