Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity
oleh: Hagit Achdout, Einat. B. Vitner, Boaz Politi, Sharon Melamed, Yfat Yahalom-Ronen, Hadas Tamir, Noam Erez, Roy Avraham, Shay Weiss, Lilach Cherry, Erez Bar-Haim, Efi Makdasi, David Gur, Moshe Aftalion, Theodor Chitlaru, Yaron Vagima, Nir Paran, Tomer Israely
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-10-01 |
Deskripsi
Influenza A virus (IAV) and SARS-CoV-2 coinfection is a possible scenario during influenza season. Here, the authors show in a mouse model that IAV infection increases the risk of severe disease upon SARS-CoV-2 infection two days later. IAV vaccination, especially antibody-dependent, protects from severe disease during coinfection.