Human adaptation and population differentiation in the light of ancient genomes

oleh: Felix M. Key, Qiaomei Fu, Frédéric Romagné, Michael Lachmann, Aida M. Andrés

Format: Article
Diterbitkan: Nature Portfolio 2016-03-01

Deskripsi

Detecting the targets of positive selection in the human genome is challenging. Here, the authors combine modern and ancient genomes to show that alleles strongly differentiated between Africans and Europeans mediated local adaptation in European populations, and were mostly contributed by ancient hunter-gatherers.