(S)-1-[3,5-Bis(trifluoromethyl)phenyl]-N-methylethylamine–(R)-2-hydroxybutanedioic acid (1/1)
oleh: Hai-Bin Zhu, Jun-Feng Ji, Hai Wang
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2009-01-01 |
Deskripsi
In the title compound, C11H11F6N·C4H6O5, a key intermediate in the synthesis of the NK1 receptor antagonist of casopitant, the F atoms of the trifluoromethyl groups are disordered over two sites with equal occupancies. In the crystal, the components are linked by bifurcated N—H...(O,O) hydrogen bonds.