Intraperitoneal microbial contamination drives post-surgical peritoneal adhesions by mesothelial EGFR-signaling
oleh: Joel Zindel, Jonas Mittner, Julia Bayer, Simon L. April-Monn, Andreas Kohler, Ysbrand Nusse, Michel Dosch, Isabel Büchi, Daniel Sanchez-Taltavull, Heather Dawson, Mercedes Gomez de Agüero, Kinji Asahina, Paul Kubes, Andrew J. Macpherson, Deborah Stroka, Daniel Candinas
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-12-01 |
Deskripsi
Abdominal surgery can often lead to complications including the formation of peritoneal adhesions and the molecular mechanisms underlying this process are still unknown. Here, the authors suggest that bacterial contamination drives adhesion formation through mesothelial EGFR signalling.