Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
oleh: Carolina Moretto Carnielli, Carolina Carneiro Soares Macedo, Tatiane De Rossi, Daniela Campos Granato, César Rivera, Romênia Ramos Domingues, Bianca Alves Pauletti, Sami Yokoo, Henry Heberle, Ariane Fidelis Busso-Lopes, Nilva Karla Cervigne, Iris Sawazaki-Calone, Gabriela Vaz Meirelles, Fábio Albuquerque Marchi, Guilherme Pimentel Telles, Rosane Minghim, Ana Carolina Prado Ribeiro, Thaís Bianca Brandão, Gilberto de Castro, Wilfredo Alejandro González-Arriagada, Alexandre Gomes, Fabio Penteado, Alan Roger Santos-Silva, Márcio Ajudarte Lopes, Priscila Campioni Rodrigues, Elias Sundquist, Tuula Salo, Sabrina Daniela da Silva, Moulay A. Alaoui-Jamali, Edgard Graner, Jay W. Fox, Ricardo Della Coletta, Adriana Franco Paes Leme
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2018-09-01 |
Deskripsi
Oral cancer has region-specific histopathological and molecular characteristics, complicating its classification by the standard tumor-node-metastasis system. Here, the authors combine discovery and targeted proteomics with IHC to identify region-specific and saliva biomarkers for oral cancer prognosis.