Tracking single particles for hours via continuous DNA-mediated fluorophore exchange

oleh: Florian Stehr, Johannes Stein, Julian Bauer, Christian Niederauer, Ralf Jungmann, Kristina Ganzinger, Petra Schwille

Format: Article
Diterbitkan: Nature Portfolio 2021-07-01

Deskripsi

The length of single-particle tracking experiments are limited due to photobleaching. Here the authors achieve long-term single-particle tracking with continuous fluorophore exchange in DNA-PAINT and use this to observe DNA origami on lipid bilayers for tens of minutes.