The Drop That Spilled the Cup: Acute Myocardial Infarction in a Young Woman with Underlying Thrombophilic Polymorphisms and Oral Contraceptive Use
oleh: Nunzio Russo, Enrico Franzì, Gianfranco Capilli, Anella Antonietta Patané, Silvia Paola Russo, Rosario Evola
| Format: | Article |
|---|---|
| Diterbitkan: | Wiley 2014-01-01 |
Deskripsi
We present the case of a 28-year-old woman who was admitted to our cardiology unit for acute coronary syndrome. Her history was notable for cardiovascular disease familiarity, active smoking, and oral contraceptive use. On further analysis, she was noted to have thrombophilic polymorphisms involving the plasminogen activator inhibitor (PAI), angiotensin-converting enzyme (ACE), and methylenetetrahydrofolate reductase (MTHFR) genes. We discuss the implications that these cofactors may have had in the genesis of the disease.