Single-cell transcriptome profiling of the stepwise progression of head and neck cancer
oleh: Ji-Hye Choi, Bok-Soon Lee, Jeon Yeob Jang, Yun Sang Lee, Hyo Jeong Kim, Jin Roh, Yoo Seob Shin, Hyun Goo Woo, Chul-Ho Kim
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
Head and neck squamous cell carcinomas (HNSCCs) undergo a stepwise progression from normal tissues. In order to better understand the molecular mechanisms behind such progression, here the authors profile HNSCC tumors at different stages using single-cell RNA-seq, and observe the role of interactions with the tumor microenvironment.