Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks
oleh: Ang Li, Jung-Hwa Cho, Brian Reid, Chun-Chih Tseng, Lian He, Peng Tan, Chao-Yuan Yeh, Ping Wu, Yuwei Li, Randall B. Widelitz, Yubin Zhou, Min Zhao, Robert H. Chow, Cheng-Ming Chuong
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-12-01 |
Deskripsi
The molecular mechanisms regulating mesenchymal cell movements are unclear. Here, the authors show in chicken feather elongation that SHH/WNT signalling establishes gap-junctions, enabling synchronized Ca2 + oscillations to emerge for and in turn coordinating directed cell migration.