Structure Elucidation and Cytotoxic Evaluation of New Polyacetylenes from a Marine Sponge Petrosia sp.
oleh: Yung-Shun Juan, Chien-Chih Lee, Chia-Wei Tsao, Mei-Chin Lu, Mohamed El-Shazly, Huei-Chuan Shih, Yu-Cheng Chen, Yang-Chang Wu, Jui-Hsin Su
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2014-09-01 |
Deskripsi
The sponge Petrosia sp. yielded five polyacetylenic compounds (1–5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1–5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines.