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AIM: To research the refraction of eyes after phacoemulsification of cataract and diffractive aspheric multifocal intraocular lens(IOL)implantation under the guidance of IOL master. METHODS: Totally 68 patients(84 eyes)with age-related cataract were selected. Routine preoperative examinations were completed, and IOLs were determined under the guidance of IOL master. All the patients underwent phacoemulsification of cataract and multifocal IOL(Tecnis AMO00)implantation. 3 months later, postoperative visual acuity and the refraction(according to the integrated refractometer)of patients were observed. RESULTS: The refraction types of these 84 eyes included 36 myopia and 48 hyperopia, with spherical and cylindrical diopter between -0.5D to +0.5D. No significant refractive error was detected. There were 64 eyes(76%)with postoperative uncorrected distance visual acuity ≥0.8, 77 eyes(92%)with best-corrected distance visual acuity ≥0.8, 58 eyes(69%)with uncorrected near visual acuity ≥0.8, 74 eyes(88%)with best-corrected near visual acuity ≥0.8, 58 eyes(69%)with intermediate visual acuity ≥0.8. CONCLUSION: Diffractive aspheric multifocal IOL provides a high level of full vision, and will be more accurately selected under the guidance of IOL master. No significant refractive error was detected after surgery, and patients were much satisfied.