A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-<i>b</i>]pyrrole and Acenaphtho[1,2-<i>b</i>]pyrrole Derivatives by Tandem Three-Component Reactions
oleh: Xiaodong Tang, Songlei Zhu, Ying Ma, Ren Wen, Lanqi Cen, Panwei Gong, Jing Wang
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2018-11-01 |
Deskripsi
A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-<i>b</i>]pyrrole and acenaphtho[1,2-<i>b</i>]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.