Methylation of PhoP by CheR Regulates <i>Salmonella</i> Virulence
oleh: Yang Su, Jianhui Li, Wenting Zhang, Jinjing Ni, Rui Huang, Zuoqiang Wang, Sen Cheng, Yue Wang, Zhixin Tian, Qiuxiang Zhou, Donghai Lin, Wenjuan Wu, Christoph M. Tang, Xiaoyun Liu, Jie Lu, Yu-Feng Yao
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-10-01 |
Deskripsi
Posttranslational modifications (PTMs) play an important role in regulating enzyme activities, protein-protein interactions, or DNA-protein recognition and, consequently, modulate many biological functions. We demonstrated that PhoP, the response regulator of PhoP/PhoQ two-component system, could be methylated on several evolutionally conserved amino acid residues.