Find in Library

Sepsis is one of the most frequent causes of death in intensive care unit (ICU) patients worldwide. According to recent reports, the incidence of sepsis has been rising at a rate of 1.5%-8% per year.1 About 9% of the sepsis develops to serious sepsis and 3% to septic shock. Although great progress has been made in the treatment of sepsis, themortality of patients with severe sepsis is still as high as 30%- 70%.2-4 Moreover, the high expenditure of sepsis management has resulted in a heavy financial burden to the government and patients.1 Therefore, howto estimatethe severity of sepsis early and apply targeted therapies timely is very important in the treatment of sepsis.