Alternative activation generates IL-10 producing type 2 innate lymphoid cells
oleh: Corey R. Seehus, Asha Kadavallore, Brian de la Torre, Alyson R. Yeckes, Yizhou Wang, Jie Tang, Jonathan Kaye
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-12-01 |
Deskripsi
Type 2 innate lymphoid cells (ILC2) are thought to be a uniform population of effector cells that produce IL-5 and IL-13. Here, the authors shown that, in mice, IL-33 can alternatively activate these cells to generate a molecularly distinct IL-10-producing subset designated ILC210.