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Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model
oleh: Ludmila A. Kasatkina, Chenshuo Ma, Mikhail E. Matlashov, Tri Vu, Mucong Li, Andrii A. Kaberniuk, Junjie Yao, Vladislav V. Verkhusha
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
Optogenetic tools can be used as in vivo imaging probes. Here the authors generate a loxP-BphP1 transgenic mouse to enable Cre-dependent temporal and spatial targeting of BphP1 expression in vivo; they show photoacoustic tomography of BphP1 expression in developing embryos and regenerating livers.