Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism
oleh: Karin Ortmayr, Sébastien Dubuis, Mattia Zampieri
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-04-01 |
Deskripsi
Aberrant gene expression in cancer coincides with drastic changes in metabolism. Here, the authors combined metabolome, transcriptome and proteome data in 54 cancer cell lines to uncover a genome-scale network of associations between transcriptional regulators and metabolites.