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In this paper, we consider the existence of positive solutions for a singular tempered fractional equation with a <i>p</i>-Laplacian operator. By constructing a pair of suitable upper and lower solutions of the problem, some new results on the existence of positive solutions for the equation including singular and nonsingular cases are established. The asymptotic behavior of the solution is also derived, which falls in between two known curves. The interesting points of this paper are that the nonlinearity of the equation may be singular in time and space variables and the corresponding operator can have a singular kernel.