Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant
oleh: Erik de Vries, Hongbo Guo, Meiling Dai, Peter J.M. Rottier, Frank J.M. van Kuppeveld, Cornelis A.M. de Haan
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2015-05-01 |
Deskripsi
In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.