Au(I)-Catalyzed Annulation of Propargyl Amine with Aldehydes: One-Pot Cascade Synthesis of 2,5-Dimethylpyrazines

oleh: Ji Su, Huixin Liu, Ruimao Hua

Format: Article
Diterbitkan: MDPI AG 2015-02-01

Deskripsi

3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh2Cy)Cl.