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In this study, nanofluid condensation and MHD flow analysis over an inclined and rotating plate are investigated respectively using Least Square Method (LSM) and numerical method. After presenting the governing equations and solving them by LSM, the accuracy of results is examined by the fourth order Runge-Kutta numerical method. For condensation, modeling results show that the condensate film thickness is reduced and in turn, the rate of heat transfer is enhanced by the addition of nanoparticles to the regular fluid. Effect of normalized thickness on velocity and temperature profiles reveals that increasing normalized thickness leads to an increase in f, f’ and a decrease in g, q. Effect of normalized thickness on k and s are similar to those of f’ and g, respectively.