Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters
oleh: Michael Landreh, Erik G. Marklund, Povilas Uzdavinys, Matteo T. Degiacomi, Mathieu Coincon, Joseph Gault, Kallol Gupta, Idlir Liko, Justin L. P. Benesch, David Drew, Carol V. Robinson
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-01-01 |
Deskripsi
Na+/H+antiporters transport sodium or lithium ions across the membrane in exchange for protons. Here the authors combine ion mobility mass spectrometry and molecular dynamics simulations to uncover a facilitating role for lipids in the transport mechanism.