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Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells
oleh: Smarajit Chakraborty, Ricksen S. Winardhi, Leslie K. Morgan, Jie Yan, Linda J. Kenney
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-11-01 |
Deskripsi
OmpR is a transcription factor activated in acid and osmotic responses of Gram-negative bacteria, leading to acidification of the bacterial cytoplasm. Here the authors use single cell pH imaging to define the role of OmpR-regulated genes in the acidification response to osmotic and acid stress of Salmonella and E. coli.