Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications
oleh: Daniel-Cristian Ioan, Ileana Rău, Mădălina Georgiana Albu Kaya, Nicoleta Radu, Marinela Bostan, Roxana Gabriela Zgârian, Graţiela Teodora Tihan, Cristina-Elena Dinu-Pîrvu, Alina Lupuliasa, Mihaela Violeta Ghica
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2020-08-01 |
Deskripsi
We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.