Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics
oleh: Erik Malmström, Ola Kilsgård, Simon Hauri, Emanuel Smeds, Heiko Herwald, Lars Malmström, Johan Malmström
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-01-01 |
Deskripsi
Sepsis can lead to multiple organ failure that could potentially be reflected by change in plasma protein abundance. Here the authors describe a proteomics strategy that allows the determination of plasma proteins tissue origin in a quantitative manner for use as biomarkers—illustrated in a mouse model of sepsis.