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Molecular sled is an eleven-amino acid vehicle facilitating biochemical interactions via sliding components along DNA
oleh: Walter F. Mangel, William J. McGrath, Kan Xiong, Vito Graziano, Paul C. Blainey
Format: | Article |
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Diterbitkan: | Nature Portfolio 2016-02-01 |
Deskripsi
Extremely compact environments can inhibit protein interactions by preventing 3-dimensional diffusion. Here the authors show that an 11-amino acid long peptide can function as a ‘molecular sled’, able to transport cargo linearly along DNA to enable interactions.